Help
A quick guide to the DGE tools: what each one does, how the filters work, and how to read the outputs.
Heatmap · Volcano · Enrichment · Gene Browser · Network
Quick start
Typical workflow (recommended).
- Start by selecting a Disease.
- Then select a Dataset (or multiple datasets in Heatmap/Gene Browser).
- Set padj cutoff and |log2FC| cutoff to filter genes.
- Click the tool action button: Compute/Generate/Run.
- Use hover/click on the plot to see details; export results via the Download buttons.
Important terms
A 1-minute reference for understanding filters.
padj: Adjusted p-value (FDR). Smaller padj means more significant.
log2FC: Log2 fold-change. Positive = up, negative = down.
|log2FC|: Magnitude filter. 0.5 is roughly a 1.41× change.
Biotype: Gene type (e.g., protein_coding, lncRNA). Filters select a subset of genes.
Tool-wise details
What each control does in each tool.